This study is being done to determine if targeted radiation therapy (stereotactic) can be given to treat liver cancer, for patient who are unable to undergo surgery, over a short period of time with a small amount of side effects.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
28
Washington University School of Medicine
St Louis, Missouri, United States
Stereotactic radiation therapy (either photon or proton) can be delivered to the liver with a less than 10% 3-month incidence of Grade 4 study related toxicity.
Time frame: Up to 90 days after end of radiation therapy
Measure the late toxicity associated with using stereotactic radiation therapy in patients with unresectable HCC and IHC.
Time frame: Up to 60 days after end of radiation therapy
Measure the local recurrence rates associated with using SBRT in patients with unresectable HCC and IHC.
Time frame: Time of treatment until recurrance or progressive disease as measured by CT/MR from baseline to recurrance or progressive disease
Measure the overall survival rates associated with using SBRT in patients with unresectable HCC and IHC.
Time frame: Baseline to time of death
Measure the response rates associated with using SBRT in patients with resectable HCC and IHC
Time frame: Baseline to the first date of recurrance or progressive disease
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