The purpose of this study is to estimate effects of different kinds, different dose of 5-HT3 receptor antagonists on prevention of hypotension after spinal anesthesia
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
100
before 5 minutes spinal anesthesia, injection of ramosetron 0.3 mg
before 5 minutes spinal anesthesia, injection of ondansetron 8 mg
before 5 minutes spinal anesthesia, injection of ondansetron 4 mg
Seoul National University Hospital
Seoul, South Korea
prevention of hypotension by calcaulation the gap between baseline mean arterial pressure and lowest mean arterial pressure measured during 30 minutes after spinal anesthesia.
comparasion of significantly difference in the gap between baseline mean arterial pressure and lowest mean arterial pressure measured during 30 minutes after spinal anesthesia.
Time frame: up to 30mins after spinal anesthesia
prevention of hypotension bycalculation the gap baseline systolic and diastolic blood pressure and lowerst systolic and diastolic blood pressure
comparasion of significantly difference in the gap between baseline systolic arterial pressure and lowest systolic arterial pressure measured during 30 minutes after spinal anesthesia and the gap between baseline diastolic arterial pressure and lowest diastolic arterial pressure measured during 30 minutes after spinal anesthesia.
Time frame: up to 30mins after spinal anesthesia
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before 5 minutes spinal anesthesia, injection of normal saline 5 ml