DA-9701 is a new prokinetic agent formulated with Pharbitis Seed and Corydalis Tuber. These plants have been used in oriental traditional medicine for the treatment of gastrointestinal maladies. In a stage 3 trial, its' efficacy has been compared to that of itopride in functional dyspepsia patients and proved to have comparable safety and efficacy. However, its' exact effect on the gastrointestinal motility has not been completely elucidated. This study will study the effects of DA-9701 on the healthy adult gastrointestinal tract.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
31
Prescribe 30mg of DA-9701(motilitone) t.i.d for 1 week and then crossover to placebo.
Administer placebo 1 tablet t.i.d for 1 week. After 1 week of washout, crossover to 30mg of DA-9701 t.i.d. for 1 week.
Seoul St Mary's hospital
Seoul, South Korea
Study the effects of DA-9701 on GI motility in healthy adult volunteers
Study the effects of DA-9701 on gastrointestinal motility in healthy adult volunteers
Time frame: 3weeks
Examine the effects of DA-9701 by Scintigraphic transit measurement
Examine the effects of DA-9701 by Scintigraphic transit measurement
Time frame: 3weeks
Examine the effects of DA-9701 by EGG/Drink test
Examine the effects of DA-9701 by EGG/Drink test
Time frame: 3weeks
Examine the effects of DA-9701 by SPECT
Examine the effects of DA-9701 by SPECT
Time frame: 3weeks
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