Open-label, randomized, crossover clinical trials for single oral dose of 60mg fimasartan and single IV infusion of 30mg fimasartan to evaluate the absolute bioavailability of Kanarb® tablet (fimasartan) in healthy subjects
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
NONE
Enrollment
16
Period 1 fisrt administration of fimasartan 60mg Period 2 second administration of fimasartan 30mg
Period 1 first administration of fimasartan 30mg Period 2 second administration of fimasartan 60mg
Inje University Busan Paik Hospital
Busan, South Korea
AUCinf, AUC, Cmax, Tmax, half-life; t1/2z, AUCt, Vdss, Cl,
Time frame: PO : 0, 0.25, 0.5, 0.75, 1, 1.5, 2, 3, 4, 5, 6, 8, 10, 12, 24, 36, 48hr, IV : 0.25, 0.5, 0.75, 1, 1.08, 1.17, 1.25, 1.5, 2, 3, 4, 5, 6, 8, 10, 12, 24, 36, 48hr
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