Chronic thromboembolic pulmonary hypertension (CTEPH) has been associated with increased morbidity and mortality. Patients with pulmonary embolism (PE) have elevated risk for development of CTEPH. It is not known, whether the location of pulmonary embolism (central vs. peripheral) nor fibrinolysis have an impact of CTEPH incidence. This study has been performed to assess the CTEPH incidence in different populations: in patients with central vs. peripheral PE and in patients with or without fibrinolysis therapy for PE.
The embolus localization during index pulmonary embolism might be of potential relevance for CTEPH development. In the present study patients with confirmed pulmonary embolism for at least 12 months will be screened for CTEPH. The incidence of CTEPH will be correlated to thrombus location (central vs. peripheral) and the index use of fibrinolysis.
Study Type
OBSERVATIONAL
Enrollment
500
Heart Center of the University Hospital of Cologne
Cologne, North Rhine-Westphalia, Germany
RECRUITINGCTEPH
Incidence of CTEPH
Time frame: participants will be followed at least one year after acute pulmonary embolism, an expected average of 5 years follow-up is estimated
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