A six-month study which investigated the effect of Ginkgo Synergy® and Choline or OPC Synergy® and Catalyn® on cognitive and immune function markers and quality of life among healthy older adults with no history of significant cognitive deficits
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
97
3 tablets 2 times per day with breakfast and dinner over 6 months
3 tablets 2 times per day with breakfast and dinner over 6 months
Clinical Research Building
Miami, Florida, United States
Cognitive Measures
The measures included the MMSE, the Stroop Color and Word Test (SCWT), the Trail Making Test Parts A and B (TMT-A, TMT-B), the Controlled Oral Word Association test (COWA), the Digit Symbol subtest of the Wechsler Adult Intelligence Scale, Third Edition (WAIS-III), and the Hopkins Verbal Learning Test-Revised (HVLT-R)
Time frame: 6 months
Quality of Life Measures
Quality of Well-Being Scale (QWBS) Medical Outcomes Study Short Form 36 (SF 36) Beck Depression Inventory (BDI) Beck Anxiety Inventory (BAI)
Time frame: 6 months
Immune Function Markers
interleukin \[IL\]-2, IL-4, IL-6, IL-8, IL-10, IL-1α, IL-1β, interferon \[IFN\]-γ, tumor necrosis factor \[TNF\]-α, monocyte chemotactic protein \[MCP\]-1, vascular endothelial growth factor \[VEGF\], and epidermal growth factor \[EGF\]
Time frame: 6 months
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