The purpose of this study is to investigate the efficacy of two different corticosteroid ointment application regimens for the treatment of eczema (atopic dermatitis).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
45
Corticosteroid ointment applied to wet skin once a day and dry skin once a day.
Corticosteroid ointment applied to dry skin twice a day.
Yale University
New Haven, Connecticut, United States
Efficacy of corticosteroid application regimen as assessed by the Eczema Area and Severity Index (EASI)
Time frame: 2 weeks
Effect of corticosteroid ointment application regimens on serum cortisol
Time frame: 2 weeks after application of topical corticosteroids
Frequency of atopic dermatitis flares in the 3 months following the two-week treatment regimen
Time frame: 3 months
Adverse effects associated with each corticosteroid application regimen
Characterize and quantify adverse effects associated with each corticosteroid application regimen.
Time frame: 3 months
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