PRospective Evaluation of Electrocardiographic Voltage Changes and Six Minute Walk Test for Predicting Readmissions in Heart Failure (PREEMT-HF Study)

Creighton University46 enrolled

Overview

Purpose of the study: To identify whether Electrocardiographic QRS voltage changes (between admission and pre-discharge) and pre discharge 6- minute walk test in patients admitted with acute heart failure can identify patients at risk for recurrent admissions for heart failure.

Primary Objective Determine the ability of EKG voltage changes and pre discharge 6-minute walk test (6-MWT) to predict repeat heart failure hospitalization (HFH) in patients admitted with acute decompensated heart failure (ADHF). Secondary Objectives 1. Determine the ability of EKG voltage changes and pre discharge 6-MWT) to predict a composite of 1 year mortality and HFH in patients admitted with ADHF. 2. Determine the ability of proportionate pulse pressure, orthostatic blood pressure changes and pre discharge inferior vena cava (IVC) diameter by portable ultrasound to predict HFH and mortality

Study Type

OBSERVATIONAL

Enrollment

Conditions

Heart Failure

Interventions

ElectrocardiogramPROCEDURE

EKG voltage changes between admission and discharge

Six minute walk testPROCEDURE

Eligibility

Sex: ALLMin age: 19 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients \> 18 years of age, admitted with a diagnosis of ADHF and fulfilling the following criteria: 1. Evidence of systemic congestion (manifested by any 2 of the following criteria: jugular venous distension, edema, pulmonary rales, Left ventricular S3, or radiographic evidence of pulmonary venous congestion) 2. Elevated Brain natriuretic peptide 3. Need for at least 1 dose of intravenous loop diuretic Exclusion Criteria: * Cardiogenic shock, Acute coronary syndromes (patients with mild elevation in troponin related to heart failure will not be excluded), patients who are admitted for another principal problem and develop ADHF in the hospital, pregnant females, end stage renal disease on hemodialysis, expected survival \< 6 months.

Locations (1)

Creighton University Medical Center

Omaha, Nebraska, United States

Outcomes

Primary Outcomes

Emergency Room Visit or Hospitalization for Acute Decompensated Heart Failure (ADHF)

Time frame: 1 year

Mortality

All cause mortality at 1 year

Time frame: 1 year

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.