Computer-assisted Cognitive Rehabilitation (CACR), Placebo CACR and Psycho-stimulants in the Treatment of ADHD

Allameh Tabatabai University34 enrolled

Overview

Current research aimed to compare the efficacy of computer-assisted cognitive rehabilitation (CACR), stimulant drugs and Placebo CACR on executive functions and clinical symptoms of children with attention deficit/hyperactivity disorder (ADHD).

The investigators administered a randomized controlled trial (RCT) through random assignment of ADHD subjects in to three different groups to compare the effects of CACR, immediate-release methylphenidate, and a Placebo CACR (i.e. some computerized tasks assumed not having any therapeutic effects) on the functioning of children with ADHD.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Attention Deficit Disorder With Hyperactivity

Interventions

Computerized cognitive rehabilitationOTHER

\- Computerized cognitive rehabilitation: 20 ninety-minute sessions of computerized cognitive rehabilitation.

RitalinDRUG

-drug therapy: 2 or 3 doses of 10 mg tablets of Immediate-release Methylphenidate (Ritalin) per day for 2 months.

Placebo CACR [PCACR]OTHER

PCACR: 20 ninety-minute sessions of Placebo computerized cognitive training.

Eligibility

Sex: MALEMin age: 7 YearsMax age: 12 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ADHD diagnosis * age between 7 and 12 * IQ \> 85 Exclusion Criteria: * sever co-morbid disorder * seizure * IQ \< 85 * disability * sever medical condition

Locations (1)

Counseling and guidence Center of the Department of education of region 9 of Tehran

Tehran, Tehran Province, Iran

Outcomes

Primary Outcomes

Persian software for the continuous performance test [CPT]

The Persian software of CPT is a visual CPT test.

Time frame: 5 months

Persian software for the Tower of London Test [TOL]

Persian TOL is a software version of tower of London test (TOL) which was developed in Iran.

Time frame: 5 months

Forward/Reversed digit span tasks from the WISC-R testing battery.

Reversed digit span from the WISC-R (Wechsler, 1974) was used to measure executive verbal WM and the forward digit span was used to measure short-term memory.

Time frame: 5 months

Raven's colored progressive matrices.

Raven's colored progressive matrices (Raven, 1995) was used to measure complex non-verbal reasoning.

Time frame: 5 months

Span board task from the Lumosity.com online software (Lumosity.com, 2012)

Time frame: 5 months

SNAP-IV scales

Time frame: 5 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.