Ovarian Stimulation and Intrauterine Insemination in Women With Polycystic Ovarian Syndrome

Mansoura University140 enrolled

Overview

The study null hypothethesis is: intrauterine insemination (IUI) does not improve pregnancy rates in women with polycystic ovary syndrome. Infertile women with pcos will receive gonadotropins for ovarian stimulation and then randomize to either IUI or timed intercourse (TI)

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

140

Conditions

Infertility Polycystic Ovarian Syndrome Intrauterine Insemination

Interventions

Intrauterine insemination (IUI)PROCEDURE

The male semen is obtained then processed by swim up technique and then introduced into the uterus by special catheter.

Eligibility

Sex: FEMALEMin age: 21 YearsMax age: 38 Years

Medical Language ↔ Plain English

Inclusion Criteria: \- women who failed to get pregnant after 6 ovulation induction cycles with clomiphene citrate (cc) alone, despite of being ovulating with cc, having patent Fallopian tubes as confirmed by hysterosalpingography and their partners had fertile semen parameters according to criteria of World Health Organization (WHO 2010) Exclusion Criteria: male factor infertility

Locations (1)

Fertility Care Unit

Al Mansurah, Eldakahlia, Egypt

Outcomes

Primary Outcomes

Live Birth Rate

Time frame: 20 months

Secondary Outcomes

Clinical pregnancy rate

Time frame: 16 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.