Comparing the Efficacy of Pregabalin and Hydroxyzine on the Anxiety Score

Inclusion Criteria: * Patients aged from 18 to 75 years * Patient schedules for insertion of long-lasting intravenous device Exclusion Criteria: * History of previous insertion of long-lasting intravenous device or central intravenous catheter * long term treatment of gabapentin or pregabalin * Hypersensitivity to pregabalin or any of the excipients * Hypersensitivity to hydroxyzine, one of its metabolites, one of the excipients, another derivative of piperazine, aminophylline or ethylene diamine. * Patient at risk of glaucoma e * Patient at risk for urinary retention * Patient severe respiratory failure * Patient at the general condition not too corrupted (ASA IV) * Renal failure with creatinin clearance \< 30 ml / min * Patient not affiliated to Social Security * Pregnant or lactating * Patients in emergency situations * Inpatient without consent