The Effect of Endurance Training on Body Composition and Insulin Sensitivity in Prostate Cancer Patients Receiving Androgen Deprivation Therapy

Inge Holm20 enrolled

Overview

The purpose of the present study is to investigate if endurance training can be used as a therapeutic action against the adverse metabolic disturbances and unfavourable changes in body composition that accompany the androgen deprivation therapy (ADT) treatment in prostate cancer patients.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Prostate Cancer

Interventions

Endurance trainingBEHAVIORAL

12 weeks of endurance training 3 times per week

Eligibility

Sex: MALEMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Prostate cancer patients receiving ADT for at least 3 months * Healthy age and BMI matched controls Exclusion Criteria: * severe cardiovascular disease * severe arthritis * severe neuropathy * severe hypertension * therapy with antidiabetic agents * VO2max \> 30.

Locations (1)

Centre of Inflammation and Metabolism, Rigshospitalet

Copenhagen, Denmark

Outcomes

Primary Outcomes

Changes in body composition and insulin sensitivity in response to training

Time frame: Body composition and insulin sensitivity are measured at baseline and after 12 weeks of endurance training

Data from ClinicalTrials.gov

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