The aim of this study was to evaluate whether survival of patients who underwent TACE with unresectable HCC can benefit from intermediate-levels of embolization.
Subjective angiographic chemoembolization endpoints (SACE) levels were developed to standardize the embolic endpoints of transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC). It determined the antegrade arterial flow and residual tumor blush as follows: I, normal-normal; II, reduced-reduced; III, reduced-none; IV, none-none. SACE level II and III indicates intermediate-levels of embolization, whereas IV indicates overembolization. The aim of this study was to evaluate whether survival of patients who underwent TACE with unresectable HCC can benefit from intermediate-levels of embolization.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
250
TACE with substasis using gelfoam
TACE with complete embolization using gelfoam
Hallym Sacred Heart Hospital
Anyang, South Korea
RECRUITINGChuncheon Sacred Heart Hospital
Chuncheon, South Korea
RECRUITINGKangnam Sacred Heart Hostpita
Seoul, South Korea
RECRUITINGSurvival rate of the subjects
Survival rate of the subjects 6 months after TACE
Time frame: 6 months after TACE
Survival rate of the subjects
Survival rate of the subjects, 12 months after TACE
Time frame: 12 months after TACE
Survival rate of the subjects
Survival rate of the subjects, 18 months after TACE
Time frame: 18 months after TACE
Survival rate of the subjects
Survival rate of the subjects, 24 months after TACE
Time frame: 24 months after TACE
Disease free survival of the subjects
Disease free survival of the subjects, 24 months after TACE
Time frame: 6, 12, 18, and 24 months after TACE
Complication rate of TACE
The incidence of infection, hemorrhage, 24 months after TACE
Time frame: 6, 12, 18, and 24 months after TACE
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