Effects of Jeju Red Horsehead Fish-based, High Protein Diet on Satiety and Incretin Hormones in Diabetes Patients

Jeju National University Hospital40 enrolled

Overview

The aim of our study is to investigate the effects of high-protein diet on satiety and incretin hormones in patients with diabetes.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Diabetes Mellitus Obesity

Interventions

High-protein dietDIETARY_SUPPLEMENT

The high-protein diet is made up of 50% carbohydrate, 40% of protein and 10% of fat, providing 480 kcal. A protein part of the high-protein diet is mostly composed of a grilled Jeju red horsehead fish, a special product of Jeju island in Korea.

Standard dietDIETARY_SUPPLEMENT

The standard diet is made up of 60% carbohydrate, 20% of protein and 20% of fat, providing 480 kcal.

Eligibility

Sex: ALLMin age: 20 YearsMax age: 79 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diabetes mellitus * Subjects signed a written informed consent form Exclusion Criteria: * Liver cirrhosis * Chronic renal disease (serum creatinine \> 2mg/dL) * Severe congestive heart failure * Significant infectious or inflammatory diseases * intractable malignant neoplasm * Pregnancy

Locations (1)

Jeju National University Hospital

Jeju City, South Korea

Outcomes

Primary Outcomes

Difference in the incremental area under the curve (iAUC) for peptide YY (PYY) after food ingestion between high-protein and standard diet groups