Congenital heart disease with need for early surgery in newborns is associated with an increased incidence in global impairment in development. The causes of these late adverse neurologic outcomes are multifactoral and include both fixed (or patient-specific factors) and modifiable factors. They relate to both the mechanism of central nervous system injury associated with congenital heart disease and its treatment. Measuring cerebral oxygenation is a promising non-invasive way of cerebral monitoring in a neonatal intensive care unit. The importance of cerebral monitoring in neonates with congenital heart problems at risk of developing neurological complications is increasingly recognized. In this way the most vulnerable moments for the newborn brain can be detected and ,if possible, lead to change in (timing of) treatment.
Study Type
OBSERVATIONAL
Enrollment
57
Neonatal Intensive Care Unit UZLeuven
Leuven, Vlaams Brabant, Belgium
Neurodevelopmental follow up at 24 months
Neurodevelopmental assessment at 24 months using Bayley scales of infant development II
Time frame: 24 months
cerebrovascular changes in the transitional phase
Cerebral oxygen saturation and autoregulatory capacity
Time frame: first 3 days of life
Association of cerebrovascular changes with short term outcome
short term outcome defined as cerebral ultrasound abnormalities at admission and discharge, ICU stay, hospital stay and mortality before discharge
Time frame: time frame of 1 admission
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