A Study Investigating Properties of the Transversus Abdominis Plane Block

Hillerod Hospital, Denmark16 enrolled

Overview

In this study we investigate the following properties of the transversus abdominis plane block in healthy volunteers: 1. Cutaneous analgesic distribution 2. Muscular affection 3. Reproducibility

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

QUADRUPLE

Enrollment

Conditions

Anesthesia, Local

Interventions

RopivacaineDRUG

Unilateral, single shot, ultrasound-guided, transversus abdominis plane block with 20 ml ropivacaine (7.5 mg/ml)

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Capable * American society of anesthesiologists classification 1 or 2 * Written informed consent Exclusion Criteria: * Age below 18 years * American society of anesthesiologists classification above 2 * Body weight below 50 kg * Body mass index \> 35 kg/m2 * Previous abdominal surgery * Acute or chronic pain * Use of pain medication less than 24 h prior to study start * Allergy to local anesthetics * Pregnancy * Breastfeeding

Locations (1)

Hillerød Hospital

Hillerød, Denmark

Outcomes

Primary Outcomes

Cutaneous analgesic distribution

Cutaneous analgesic distribution 90 min after transversus abdominis plane block administration

Time frame: 90 min

Secondary Outcomes

Muscular affection of the transversus abdominis plane block

Abdominal wall muscle affection of the transversus abdominal plane block measured by ultrasonography under standardized conditions

Time frame: 90 min

Reproducibility of the transversus abdominis plane block

Reproducibility of the transversus abdominis plane block with respect to: 1. Cutaneous analgesic distribution 2. Abdominal wall muscle affection measured in the same individual separated by at least 2 days

Time frame: At least 2 days

Data from ClinicalTrials.gov

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