Impact of Drains on Postoperative Nausea and Vomiting After Thyroid Surgery

Kantonsspital Liestal139 enrolled

Overview

Wound Drains after Thyroid- and Parathyroid Surgery Impact on Postoperative Nausea and Vomiting (PONV)

Postoperative nausea and vomiting (PONV) is common after thyroid surgery. Many patients describe PONV as more irritant in the postoperative course than the endured pain. Postoperative drains are put after thyroid surgery to early recognize bleeding and to collect wound secretion to avoid pressure on the trachea. Whether wound drains do impact on PONV is not known. Therefore, we tested the impact of wound drains on PONV after thyroid- and parathyroid surgery in a randomized controlled clinical trial.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Masking

NONE

Enrollment

139

Conditions

Postoperative Nausea and Vomiting

Interventions

Placement of a wound drain post surgery (Redon; Medicoplast)DEVICE

The wound drain, type Redon Drainage 3.0 mm in diameter

No-drain after surgeryOTHER

After surgery, no drain was put

Eligibility

Sex: ALLMin age: 18 YearsMax age: 95 Years

Medical Language ↔ Plain English

Inclusion Criteria: * older than 18 years of age * informed consent * planed thyroid- or parathyroid resection * euthyreostatic preoperative condition Exclusion Criteria: * younger than 18 years of age * pregnancy * no informed consent * retrosternal struma * known postoperative nausea and vomiting prior to surgery * severe and life threatening systemic health issues

Locations (1)

Kantonsspital Liestal

Liestal, Basel-Landschaft, Switzerland

Outcomes

Primary Outcomes

Assessment of post-operative nausea using visual analogue scale (VAS)

The development of postoperative nausea was determined using a standard visual analogue scale (VAS) with range of 0 to 10. 0 indicated no nausea, 10 indicated very severe nausea. The patients indicated their felt degree of nausea a number between 0 to 10.

Time frame: 24 hours post surgery

Assessment of postoperative vomiting using visual analogue scale (VAS)

The development of postoperative vomiting was determined using a standard Visual analogue scale (VAS) with range of 0 to 10. 0 indicated no nausea, 10 indicated very severe nausea. The patients indicated their felt degree of vomiting indicating a number between 0 to 10. The number of vomiting was counted within the first 48h post surgery

Time frame: 24 hours post surgery

Assessment of post-operative nausea using visual analogue scale (VAS)

Time frame: 48 hours post surgery

Assessment of postoperative vomiting using visual analogue scale (VAS)

Time frame: 48 hours post surgery

Secondary Outcomes

Antiemetic therapy post surgery in patients with and without postoperative drainage

In the postoperative course, we counted the amount of anti-emetic interventions for patients post surgery over the first 48 hours. The givage of anti-emetic drugs was based on a prior determined protocol, that was strictly followed. The protocol was as follows for antiemetic drugs: First line Drug: Tropisetron 2 mg i.v. when patient is vomiting, max. twice a day. Second line therapy: Haloperidol 0.5 mg i.v. with a maximum of 3 mg every 24 hours, when first line therapy is not sufficient. The change to second line therapy is controlled by the study physician.

Data from ClinicalTrials.gov

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