Collection of Blood and Bone Marrow From Patients With Aplastic Anemia for Analysis of Adhesion Molecules, Chemokines and Their Receptors

Shandong University

Overview

This study is designed to collect bone marrow and/or peripheral blood cells and plasma, for the analysis of adhesion molecules, chemokines and their receptors from newly-diagnosed aplastic anemia patients, and patients treated with antithymocyte globulin plus cyclosporine

Study Type

OBSERVATIONAL

Conditions

Aplastic Anemia Healthy

Eligibility

Sex: ALLMin age: 16 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * patients who fulfilled entry criteria of acquired aplastic anemia age range 16-70 years Exclusion Criteria: * Patients complicated with diabetes, tumor, pregnancy, active infection, or connective tissue diseases, such as systemic lupus erythematosus.

Locations (1)

Qilu Hospital, Shandong University

Jinan, Shandong, China

Outcomes

Primary Outcomes

hematologic response

hematologic response at 6 months following antithymocyte globulin plus cyclosporine treatment, defined as no longer meeting the criteria for severe aplastic anemia

Time frame: 6 months following antithymocyte globulin plus cyclosporine treatment

Data from ClinicalTrials.gov

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