The regulation of our food intake is on the short-term guided by appetite and satiety signals generated by the sight and consumption of food. Food intake is not only regulated by appetite and satiety signals - external cues also play an important role. It has been observed that food intake and the pleasure derived from consumption is affected by manipulation of the external cues. The investigators will assess the contribution of food anticipation (calorie information) and actual consumption of a test food (calorie intake) on in satiety responses (such as ghrelin responses, appetite and subsequent food intake). The investigators expect the information on the amount of calories, rather than the actual amount of calories in the food, to predict the ghrelin responses and the subsequent intake of a second meal.
In a randomized cross-over design with 4 conditions, all participants will consume twice the low-caloric food (once with the low-calorie information and once with the high-calorie information) and twice the high-caloric food (again, once with the low-calorie information and once with the high-calorie information) in a randomized order.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
12
all participants consumed twice the low-caloric food (once with the low-calorie information and once with the high-calorie information)
all participants consumed twice the high-caloric food (once with the low-calorie information and once with the high-calorie information)
Uppsala University
Uppsala, Sweden
Food intake
Time frame: 60 min (Ad libitum test meal after 1 hr)
Serum concentrations total ghrelin
Time frame: 60 min (4 samples - every 20 min)
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