The purpose of this project is to study the effects of gabapentin on pain control in the perioperative and post-operative period of total knee arthroplasty.
Being able to understand and better control pain in patients undergoing total knee arthroplasty will help in many different areas of medicine. Gabapentin is one pain control modality that has been used by many different orthopaedic surgeons with excellent retrospective results. Gabapentin, however, has never been studied, to the investigators knowledge, in a prospective randomized fashion in the United States for total knee arthroplasty. This study will be the first of its kind to truly compare the effects of gabapentin, a drug that has been proven safe in many other areas of medicine, with placebo for total knee arthroplasty by analyzing post-operative narcotic usage, function and sleep quality.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
50
Gabapentin 600mg PO pre-operatively and continued postoperatively 300 mg PO q8 hours x 3 days.
TTUHSC Orthopaedic Surgery MS 9436
Lubbock, Texas, United States
Patient Pain Scores
Patient's pain assessed by the Visual Analog Scale (VAS - Units on a scale) on postoperative days 0, 1 and 2. Scale range: 0-100 Higher Values = More Pain
Time frame: 3 days
Narcotics Consumption
Narcotics consumption was recorded on postoperative days 0, 1, and 2.
Time frame: 3 days
Knee Range of Motion
Patient knee range of motion was assessed on postoperative days 0, 1 and 2.
Time frame: 3 days
Patient Restfulness
Percentage of self reported patient restfulness was recorded on postoperative days 0, 1 and 2.
Time frame: 3 days
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