Wavefront-guided LASIK for Correction of Myopia

Aarhus University Hospital

Overview

Laser in situ keratomileusis is a successful procedure for the treatment of low to moderate myopia. Advances over the last decade have allowed LASIK to also correct higher order wavefront aberrations. In low myopia, there seem to be a minor effect of such wavefront-guided treatment. However, it remains to be established whether there is a beneficial effect in higher degrees of myopia. The study aims to determine whether myopic subjects (-6 to -10 diopters) with higher-than-average preoperative higher-order aberrations have benefit of wavefront-guided treatment. Subjects are randomized to wavefront-guided treatment in one eye, and conventional treatment in the other.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Conditions

Myopia

Interventions

Laser in situ keratomileusis (LASIK)PROCEDURE

Wavefront guided treatment in one eye, conventional in the other.

Eligibility

Sex: ALLMin age: 20 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 20 to 50 years * No known ocular or systemic disease * Not pregnant or breastfeeding * Myopia between -6.0 and -10.0 diopters * Astigmatism below 2.0 diopters * Difference of less than 1.0 diopters in spherical equivalent between eyes * Normal corneal topography * Corneal thickness sufficient for planned treatment Exclusion Criteria: * Patients that do not fulfill inclusion criteria * Insufficient quality of ocular wavefront measurement

Locations (1)

Department of Ophthalmology, Aarhus University Hospital

Aarhus, Denmark

Outcomes

Primary Outcomes

Visual acuity

Time frame: 12 months

Secondary Outcomes

Ocular higher order aberrations

Hartmann-Schack wavefront aberrometry using the Zeiss Meditec WASCA

Time frame: 12 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.