In this study of endometriosis patients we compare a common treatment of surgical therapy and medical treatment for 3 months (Zoladex) with patients receiving only surgical therapy. In both cases they immediately start In Vitro Fertilization (IVF) treatment.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
120
after surgical vaporization patients are treated with Zoladex for 3 months before starting IVF treatment
AZ Jan Palfijn
Ghent, Oost-vlaanderen, Belgium
Number of Metaphase II Cells (MII)
number of MII cells retrieved
Time frame: 3 weeks
Pregnancy Rate
The number of ongoing pregnancies obtained which still is the most important issue for the patients.
Time frame: 12 weeks
Good Embryo Quality
The development of the embryo at the time of transfer on day 3. Good quality is defined by more than 7 cells and less then 20% fragmentation on day 3.
Time frame: 3 days after oocyte retrieval
Number of Pro Nuclear Cell (2PN)
number of 2PN
Time frame: 1 day after oocyte retrieval
Number of Cryopreserved Embryos
number of blastocytes that can be cryopreserved
Time frame: 1 week after oocyte retrieval
Total Follicle Stimulating Hormone (FSH) Dose
total dose of FSH needed at the end of stimulation
Time frame: 3 weeks
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