Topography guided laser treatment enables the surgeon to correct higher order aberrations in corneas with irregular astigmatism. Several case reports and small uncontrolled trials have been published on the combination of this treatment with corneal cross linking (CCL) in patients with ectatic corneal diseases. This randomized study will evaluate the safety and efficacy of a combined treatment of corneal cross linking with a partial topography guided excimer laser treatment in eyes with progressive ectatic corneal diseases.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
30
A topography guided excimer laser treatment will be performed prior to CCL in one session.
A standard corneal cross linking procedure will be performed in this arm.
Medical University of Vienna, Department of Ophthalmology
Vienna, Austria
Safety (Pachymetry, K-readings)
Time frame: 1 year
uncorrected visual acuity (UVCA)
Time frame: 1 year
best corrected visual acuity (BCVA)
Time frame: 1 year
Progression of ectatic disease (by use of maximum keratometry readings = Kmax)
Time frame: 1 year
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