In this study the investigators compare the traditional way of triggering with a new way in patients with Poly Cystic Ovary Syndrome (PCOS). This to reduce the risque of Ovary Hyper Stimulation Syndrome (OHSS) in In Vitro Fertilization/ IntraCytoplastic Sperm Injection (IVF/ ICSI) treatment. The investigators also compare the number of mature oocytes, embryo's and pregnancy rate.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
120
ovulation induction with GnRh agonist and 1500E hCG one hour after egg retrieval
AZ Jan Palfijn
Ghent, Oost-vlaanderen, Belgium
MII oocytes
The number of mature oocytes retrieved after stimulation without creating OHSS
Time frame: patients will be followed during the stimulation with an average of 10 days
2 Pro Nuclei (2PN) fertilization
laboratory follow up of the fertilized egg during the first 24h
Time frame: 24h after ICSI
implantation rate
The number of pregnancies obtained wich still is the most important issue for the patients
Time frame: 12 weeks
OHSS
patient follow up according to subjective complaints and objective measures
Time frame: one month with oocyte retrieval in the middle
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