Evaluation of the Effectiveness of Two Marketed Multi-Purpose Solutions for Silicone Hydrogel Contact Lenses - Study 1

Inclusion Criteria: * Wear single vision sphere silicone hydrogel contact lenses (CooperVision™ Biofinity®, Alcon® Air Optix® Aqua, Bausch+Lomb® PureVision™ or ACUVUE® Oasys™) on a daily wear basis (a minimum of 8 hours per day, 5 days a week) for at least one month prior to Visit 1; * Willing to wear lenses on a daily wear basis (a minimum of 8 hours per day, 5 days a week) for the duration of the study, and wear lenses for 16 hours on two days during the study; * Must have habitually used a Biguanide preserved multi-purpose solution (other than Biotrue) for at least 30 days prior to Visit 1; * Vision correctable to 20/30 Snellen (feet) or better in each eye at distance with pre-study contact lenses at Visit 1; * Have access, capability and willingness to review and answer text messages; * Read, sign, and date IRB/IEC approved informed consent and privacy document before enrollment; * Willing to follow the study procedures and visit schedule; * Other protocol-defined inclusion criteria may apply. Exclusion Criteria: * Need to wear lenses on an extended wear (i.e. overnight) basis during the study; * Known sensitivity or intolerance to Biguanide, polyquaternium-1 (POLYQUAD), or ALDOX preserved lens care products; * Monocular (only one eye with functional vision) or fit with only one lens; * Wearing toric or multifocal contact lenses or fit with monovision; * Use of additional lens care products other than a Biguanide preserved multipurpose solution such as daily or enzyme cleaners within the one week prior to Visit 1; * Use of topical ocular over-the-counter (OTC) or prescribed topical ocular medications, with the exception of rewetting drops, within 7 days prior to Visit 1; * Abnormal ocular condition observed during the Visit 1 slit-lamp examination; * Current or history of ocular infections or severe inflammation within 6 months prior to Visit 1; * Ocular surgery within the 12 months prior to Visit 1; * Participation in any other clinical trial within 30 days of enrollment; * Other protocol-defined exclusion criteria may apply.