Patient suffering a Transient Ischemic Attack (TIA) or stroke are subsequently at high risk of a new stroke, however, poor adherence to secondary prevention medications occurs frequently within this patient group. The purpose of this study is to evaluate whether a complex tailored pharmacist intervention will lead to increased adherence to secondary stroke prevention medications and less new stroke events when compared to a usual care group. Interventions focus on motivational interviewing, medication review and telephone follow up.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
211
Odense University Hospital
Odense C, Denmark
Medication Adherence to antiplatelets, anticoagulants and statins measured by proportion of days covered (PDC).
Time frame: One year from inclusion
For antiplatelets, anticoagulants and statins: Percent of patients that are at least 80% adherent (PDC>0.8)
Time frame: 1 year from inclusion
Medication Adherence to antihypertensives measured by proportion of days covered (PDC)
Time frame: One year from inclusion
Percent of patients that are at least 80% adherent (PDC>0.8) to antihypertensives
Time frame: One year from inclusion
Non-persistence with thromboprophylactic agents ( antiplatelets, anticoagulants, statins and antihypertensives) measured by percent of patients that are not supplied with medication for more than 3 continuous months
Time frame: One year from inclusion
Accept rate for thromboprophylactic agents measured by percent of patients starting treatment within 0-90 days after discharge.
Time frame: 3 months from discharge
Composite endpoint: stroke, myocardial infarction or cardiovascular death
Time frame: One year from inclusion
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