To investigate: 1. Associations between miRNA and insulin signaling-related gene expressions in abdominal adipose tissues in obese subjects. 2. Differences in miRNAs expressed by intrabdominal omental adipose tissues between genders.
Compared the differences in microRNA expressions of abdominal adipose tissue in morbid obese male and female subjects to elucidate the possible regulatory role of microRNA in insulin signaling-related gene expression levels and its association with biochemical markers. We hope to find a miRNA that can be used to predict the syndrome associated with obesity.
Study Type
OBSERVATIONAL
Enrollment
20
Paired samples of abdominal subcutaneous and intrabdominal omental adipose tissue were obtained from men and women who underwent bariatric surgery.
Taipei Medical University Hospital
Taipei, Taiwan, Taiwan
MicroRNA expression in abdominal omental adipose tissues
MicroRNA-125a-3p expression in abdominal omental adipose tissues is associated with insulin signaling-related gene expression levels in morbid obesity
Time frame: up to 28 weeks
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