Influence of Inspiratory Flow Pattern on Exchange of Carbon Dioxide in Humans Without Primary Lung Disease

Region Skane8 enrolled

Overview

The purpose of this study is to investigate how inspiratory flow pattern influences CO2 elimination in people without primary lung disease. The hypothesis is that a long mean distribution time, caused by a long postinspiratory pause and high end-inspiratory flow, will promote CO2 exchange in the alveoli.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Pulmonary Gas Exchange Carbon Dioxide

Interventions

Altered breathOTHER

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * No known primary lung disease Exclusion Criteria: * Primary lung disease

Locations (1)

Division of Brain, Heart and Lungs, Neurosurgical Clinic, Skane University Hospital, Lund

Lund, Skåne County, Sweden

Outcomes

Primary Outcomes

Carbon dioxide elimination in a ventilator assisted breath.

Time frame: 30 minutes

Secondary Outcomes

Blood CO2 concentration.

Time frame: 30 minutes

Data from ClinicalTrials.gov

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