This cross-over design study will evaluate the onset of action, efficacy, and duration of botulinum toxin A treatment on forehead/glabellar rhytid complexes with and without subsequent muscle contraction.
In this cross-over design study, the investigators will evaluate whether active muscle contraction following Botox® injection of the forehead/glabellar rhytid complex will impact the onset of action, efficacy, and duration of Botox® treatment.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
25
Forehead will be injected with Botox.
Northwestern University Feinberg School of Medicine, Department of Dermatology
Chicago, Illinois, United States
Measurement of Forehead Wrinkles with Honeck Four Point Rating Scale
A single dermatologist will rate each photograph of the subject's forehead/glabellar rhytid complex at baseline, 1 day, 2 days, 3 days, 4 days, 7 days, 2 weeks, 7 months and 1 day, 7 months and 2 days, 7 months and 3 days, 7 months and 4 days, 7 months and 7 days, and 7 months and 2 weeks. A glabellar wrinkle score and a forehead wrinkle score will be assigned to each photograph. The dermatologist will not know at what point in time the photographs were taken.
Time frame: 13 months
Number of Participants with Adverse Events
Side effects and adverse events will be assessed
Time frame: 13 months
Level of Satisfaction
Patients will be asked to rate their satisfaction
Time frame: 7 months
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