Immune Response in the SAPHO Syndrome

Assistance Publique - Hôpitaux de Paris39 enrolled

Overview

The aetiology of SAPHO syndrome seems to involve genetic, infectious and immunological components. The investigators examined innate and adaptative immune responses in SAPHO syndrome as compared with psoriatic arthritis and rheumatoid arthritis.

Study Type

OBSERVATIONAL

Enrollment

Conditions

SAPHO Syndrome

Eligibility

Sex: ALLMin age: 1 YearMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis of SAPHO syndrome * Must have bone lesions Exclusion Criteria: * Infliximab treatment

Outcomes

Primary Outcomes

IL-8 production by PMN

Time frame: 24 h

Secondary Outcomes

TNFalpha production by PMN

Time frame: 24 h

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.