Pharmacokinetic/Pharmacodynamic Study of Ilaprazole to Evaluate the Effect of CYP Genetic Polymorphism

Inclusion Criteria: * healthy adult volunteer between 20 and 45 years of age and within 20% of ideal body weight * No congenital or acquired chronic disease * appropriate for the study judging from examinations (hematology, chemistry, urinalysis and so on), vital sign and ECG results * sign the informed consent form prior to study participation Exclusion Criteria: * received any metabolizing enzymes or transporters inducing or inhibiting drugs like barbiturates within 1 month prior to the date of first drug administration * history of hypersensitivity against drugs or clinically significant allergic diseases * abnormal laboratory results * positive result for helicobacter pylori infection from the Urea Breath Test * alcohol or drug abuser * pregnant or lactating * donated whole blood within 60days prior to the study