Dextrose Infusion by Burettes Versus Dextrose Boluses in Prevention of Neonatal Hypoglycemia

Makerere University140 enrolled

Overview

NULL HYPOTHESIS • There is no difference in the incidence of hypoglycemia among preterms receiving either two hourly 10% dextrose boluses or 10% dextrose infusion by burettes during the 72 hours of admission in Special Care Unit- Mulago Hospital. ALTERNATE HYPOTHESIS • Use of two hourly 10% dextrose boluses increases the incidence of hypoglycemia by 30% compared to 10% dextrose infusion by burettes among preterms admitted to Special Care Unit in the first 72 hours of admission.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

140

Conditions

Once a Preterm Developed Hypoglycemia, no More Blood Glucose Was Measured During the Study Period.

Interventions

10% dextroseDRUG

Eligibility

Sex: ALLMax age: 24 HoursHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: \- SELECTION CRITERIA Inclusion criteria * Preterms whose care givers/ mothers gave informed consent * Preterms whose age was \< 24 hours of life * Preterms with birth weight ≥1kg * Preterms with random blood sugar ≥ 2.6 mmol/l at admission into SCU. Exclusion Criteria * Absence of a biological mother or abandoned baby * Presence of gross congenital abnormalities. * Very sick (Apgar score ≤ 5 at 5 minutes

Locations (1)

Mulago Hospital

Kampala, Mulago, Uganda

Outcomes

Primary Outcomes

Incidence proportion of hypoglycemia

Time frame: 3months

Secondary Outcomes

survival measured as a proportion

Time frame: 3months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.