To compare the polyp and adenoma detection rate of MOVIPREP versus an oral Sodium Picosulfate/Magnesium Citrate solution.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SCREENING
Masking
SINGLE
Enrollment
398
Klinikum Aschaffenburg
Aschaffenburg, Germany
Polyp detection rate
Polyp detection rate defined as number of patients with at least one polyp or flat lesion as recorded by the endoscopist
Time frame: At colonoscopy
Adenoma Detection Rate (ADR)
ADR, (including flat lesions) defined as number of patients with at least one adenoma as recorded by the pathologist in relation to the total analysis population
Time frame: At the Colonoscopy
ADR and PDR by location
ADR and PDR by location: * left sided (rectum, colon sigmoideum, colon decendens, left half of colon transversum * right-sided (right half of colon transversum, colon ascendens, caecum
Time frame: at the colonoscopy
Cancer detection rate
Cancer detection rate, defined as number of patients with at least one malignancy in relation to the total analysis population
Time frame: at the colonoscopy
Flat lesion only detection rate
Flat lesion only detection of the patients
Time frame: at the colonoscopy
Advanced risk lesion detection rate
Advanced risk lesion detection rate (lesions \>1 cm, low grade and/or villous
Time frame: at the colonoscopy
Colonoscopy completion rate
The rate of colonoscopy completion
Time frame: at the colonoscopy
Colon cleansing quality
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Colon cleansing quality as reported by the gastroenterologist, according to the Harefield Cleansing Scale©
Time frame: at the colonoscopy
Acceptability and tolerability of medication using patient questionnaires
The acceptability and tolerability of the study medication taken by the patients throughout the study using specified patient questionnaires
Time frame: Throughout the study