Klinefelter syndrome is the most common sex-chromosome disorder in men with a prevalence of 1 in 660 men. The syndrome is associated with hypogonadism. Many patients with Klinefelter syndrome have psychological complaints and physical discomfort. Some patients report a positive effect of testosterone treatment, whereas others do not. The aim of this study is: (i) To investigate quality of life in patients with Klinefelter syndrome. (ii) To investigate functional, physical and mental health in patients with Klinefelter syndrome. Questionnaire concerning mental and physical health and life quality are sent out to patients with KS and to age-, educational- and zipcode-matched men from the general population. The questionnaire include questions about housing, income, marital status, fatherhood, medication, chronic disease,school and education, attachment to the labor, sexual and erectile function, life quality, mental and physical health, satisfaction with life and symptoms of attention deficits hyperactivity disorders.
Study Type
OBSERVATIONAL
Enrollment
452
Medical Department M, Aarhus Universityhospital
Aarhus, Denmark
Quality of life
Quality of life score is measured with the WHOQOL-Brief questionnaire
Time frame: 3 month
Satisfaction with life
Satisfaction with life is measured with the SWLS - Satisfaction with Life Scale
Time frame: 3 month
ADHD symptoms
ADHD symptoms are measured by Adult ADHD Self-Report Scale (ASRS-v1.1) Symptom Checklist
Time frame: 3 month
General health
General health is measured by SF-36 questionnaire
Time frame: 3 month
Erectile function
Erectile function is measured by the International index of erectile function (IIEF-5) as a diagnostic tool for erectile function.
Time frame: 3 month
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