The purpose of this study is to determine the incidence of residual curarization in PACU and relevant risk factors.
In the last twenty years, residual curarization in PACU (Post Anesthesia Care Unit) has become a common problem in clinical practice and poses high risk to patients. The residual curarization incidence of Neuromuscular blocking agents (NMBA) varies very much between different studies. These differences indicates the necessity of further study. In China, there is no common view of the harmfulness of residual curarization and its complications. The consensus on the necessity of neuromuscular transmission monitoring and neuromuscular blockade antagonist has not been reached yet. There is also no similar large-scale survey in China. In this case, the investigators conduct this large scale multicentre study, which is designed to learn the incidence of residual curarization and its complications. Further analysis of risk factors will also been made. All these efforts are hoped to fill the data gap and provide reliable evidences for rational use of NMBA.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
6,090
Administrative protocol of Vecuronium Bromide is determined by each caregiver's clinical experience.
Administrative protocol of rocuronium is determined by each caregiver's clinical experience.
Administrative protocol of cisatracurium is determined by each caregiver's clinical experience
incidence of TOFr<0.9
Once tracheal extubation is performed after the surgery is over, monitor the neuromuscular transmission function (TOF ratio) immediately.
Time frame: From tracheal extubation to 1 minute after extubation
Incidence of TOFr<0.9
When patients arrive at PACU(an expected average of 15 minutes after surgery is over), monitor the neuromuscular transmission function (TOF ratio) immediately
Time frame: One minute after arriving at PACU
Incidence of TOFr<0.7
Once tracheal extubation is performed after the surgery is over, monitor the neuromuscular transmission function (TOF ratio) immediately.
Time frame: From tracheal extubation to 1 minute after extubation
Incidence of TOFr<0.7
When patients arrive at PACU(an expected average of 15 minutes after surgery is over), monitor the neuromuscular transmission function (TOF ratio) immediately
Time frame: One minute after arriving at PACU
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