The primary purpose of this study is to estimate the relative bioavailability and food effect of a PF-05089771 capsule.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
12
Oral dispersion TS formulation- fasted
Capsules TS formulation- fasted
Pfizer Investigational Site
Brussels, Belgium
Maximum concentration (Cmax) for PF-05089771 in plasma (measured in ng/mL)
Time frame: days 1-2
AUClast = Area under the curve from the time of dosing to the last data point taken (ng.hr/mL)
Time frame: days 1-2
AUCinf = Area under the curve from the time of dosing extrapolated to infinity (ng.hr/mL)
Time frame: days 1-2
Tmax = Time of maximum concentration of PF-05089771 in plasma (hr)
Time frame: days 1-2
t½ = Elimination half life of PF-05089771 (hr)
Time frame: days 1-2
evaluation of safety clinical laboratory tests, vital signs, ECGs, physical examinations and adverse event monitoring.
Time frame: days 1-2
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