The trial aims to record possible effects of a supplementary treatment with ivy leaves dry extract on different lung function parameter, on bronchial hyperreactivity, on individual markers of asthmatic inflammation and on the clinical symptom profile. The hypothesis is, that the additional therapy might improve these parameters and might help to optimize asthma therapy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
30
5 ml twice daily po
5 ml per os twice daily
Universitätsklinikum Carl Gustav Carus, Kinderklinik
Dresden, Saxony, Germany
RECRUITINGMEF75-25 before bronchodilation - relative change
MEF75-25 will be measured at every time point of the study and relative changes will be followed
Time frame: every 4 weeks
FEV1 before bronchodilation - relative change
FEV1 before bronchodilation will be measured at every study visit and changes will be documented
Time frame: every 4 weeks
MEF75-25 before bronchodilation - absolute change
Time frame: every 4 weeks
FEV1 before bronchodilation - absolute change
FEV1 before bronchodilation will be measured every visit and changes documented
Time frame: every 4 weeks
Emergency treatment (beta agonist demand)
Emergency treatment (beta agonist demand)will be documented daily at home and checked at every study visit
Time frame: daily
Number of days with asthma symptoms
Number of days with asthma symptoms will be documented daily and checked at every study visit.
Time frame: daily
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