Intracoronary Imaging With NIRS-IVUS to Characterize Arterial Plaques

Corewell Health West500 enrolled

Overview

To characterize atherosclerotic coronary artery plaques using advanced intra-coronary imaging with a combined near-infrared spectroscopy and intravascular ultrasound catheter before and after percutaneous intervention

This study is being performed to characterize the composition and morphologic characteristics of atherosclerotic coronary artery plaques with intra-coronary near-infrared spectroscopy and intravascular ultrasound in patients undergoing percutaneous coronary intervention.

Study Type

OBSERVATIONAL

Enrollment

500

Conditions

Coronary Artery Disease

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Subject is at \> 18 years of age 2. Subject presents to the catheterization laboratory to undergo clinically-indicated, invasive coronary angiography 3. Subject is willing and able to provide informed written consent 4. Subject is found to have ≥ 1 severe coronary artery stenosis by invasive angiography and percutaneous coronary intervention is planned for definitive treatment or found to have ≥ 1 intermediate coronary artery stenosis and IVUS planned for lesion assessment 5. Coronary anatomy is deemed suitable for combined NIRS-IVUS by the interventional cardiologist performing invasive angiography and intervention Exclusion Criteria: 1. Subject is pregnant or suspected to be pregnant 2. Subject is unable to provide informed consent 3. Subject has coronary artery anatomy deemed by interventionalist as unsuitable for NIRS-IVUS

Locations (1)

Spectrum Health; Frederik Meijer Heart &Vascular Institute

Grand Rapids, Michigan, United States

Outcomes

Primary Outcomes

MACCE

Time frame: 5 year

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.