A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), Food Effect of AMG 357 in Healthy Subjects

Inclusion Criteria: * Healthy Adult subjects between 25 and 55 years old * Body mass index (BMI) between 18 and 32 kg/m2 * Normal or clinically acceptable physical examination, clinical laboratory values, and ECG * Additional inclusion criteria apply Exclusion Criteria: * Any history or evidence of a clinically significant disorder, condition or disease that would pose a risk to subject safety. * Additional exclusion criteria apply