The purpose of this study is to evaluate the efficacy of changing to DuoTrav® (Travoprost 0.004%/Timolol 0.5%) from prior prostaglandin analogue or beta-blocker monotherapy in Russian glaucoma patients with open-angle glaucoma or ocular hypertension whose intraocular pressure (IOP) is uncontrolled while on their current treatment.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
One drop self-administered topically to the study eye(s) once daily every evening at 8:00 pm for 12 weeks
Change from baseline (Day 0) in intraocular pressure (IOP) at final visit (Week 12)
As measured by Goldmann applanation tonometry. If only one eye qualifies for inclusion and treatment, this eye will be selected for analysis. If both eyes qualify and are treated, the worse evaluable eye will be selected for analysis. The worse eye will be the eye with the higher IOP at the screening/baseline visit. If both eyes are equal, the right eye will be selected for analysis.
Time frame: Baseline (Day 0), Week 12
Percentage of subjects who reach target IOP (≤18 mmHg)
As measured by Goldmann applanation tonometry.
Time frame: Week 12
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