Bioefficiency of of Conventional Fish and Vitamin D Fortified Fish

Ulrike Lehmann53 enrolled

Overview

The aim of this study is to investigate the bioavailability of conventional and vitamin D fortified fish as measured by the increase of the specific hydroxy form by 25(OH)D3.

Study design: Human volunteers will receive conventional fish or vitamin D fortified fish for a period of 4 weeks. At baseline and after 4 weeks, 25(OH)D3 will be measured in serum as the main outcome variables. Additional outcome variables are the Ca concentration in serum, PTH concentration in serum. Groups/Cohorts Assigned Interventions 1. Placebo group receiving conventional fish 2. intervention group receiving vitamin D fortified fish

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

DOUBLE

Enrollment

Conditions

Vitamin D Deficiency

Interventions

vitamin D fortified fishOTHER

fish containing vitamin D3

conventional fishOTHER

fish containing low concentrations of vitamin D3

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 18 years * healthy Exclusion Criteria: * supplementation of vitamin d and calcium * hypercalcemia * hypercalciuria * chronical illness (diabetes, kidney diseases, cardiovascular diseases) * serum-creatinine above 115 mmol/l * pregnancy or breastfeeding women

Locations (1)

Naturwissenschaftliche Fakultät

Halle, Saxony-Anhalt, Germany

Outcomes

Primary Outcomes

change of 25-hydroxvitamin D

Time frame: after 4 weeks of consumption

Data from ClinicalTrials.gov

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