Effect of Exercise as Non-surgical Treatments on Time to Total Hip Replacement Surgery

University of Southern Denmark110 enrolled

Overview

The aim of this trial is to test the hypothesis that patients with severe hip osteoarthritis postpone time to hip replacement surgery following participation in a patient education and supervised exercise program when compared to patients receiving patient education alone.

Hip replacements are performed at an increasing rate, also in younger and less disabled patients. Recent studies indicate non-surgical interventions being effective in reducing pain and disability also at later stages of disease when hip replacement is considered. Possible, non-surgical treatments can be used to postpone hip replacement. The effect of education and supervised exercise on time to hip replacement is largely unknown

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

110

Conditions

Osteoarthritis

Interventions

Supervised exerciseOTHER

Patients in the exercise groups will receive two types of exercise, delivered on separate days. One type of exercise is individualized, goal-based neuromuscular training (NEMEX-TJR) in groups with progression guided by the patient's neuromuscular function. The other type of exercise is individualized, intensive resistance training (RT) in groups with each exercise progression guided by load. Each of the two types of exercise will be offered weekly during the 12 week intervention period in sessions lasting 60-70 minutes. Thus, the entire exercise intervention consists of 24 sessions

Patient educationOTHER

The patient education program is designed to educate the patients about hip osteoarthritis during 3 sessions of 90 min. duration

Eligibility

Sex: ALLMin age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 40 years and older * Indication for total hip arthroplasty * Residency within local municipal or willing to commute Exclusion Criteria: * Inflammatory joint disease * Earlier ipsilateral proximal femur fracture * Hip pain \< 3 months * Neuropathy or neuromuscular disease * Malignant disease * Diseases where a moderate level of physical exercise is contraindicated * Unable to speak or read Danish * Unable to participate for other reasons * Refuse to participate

Locations (2)

Dept. of Orthopedic Surgery and Traumatology, Odense University Hospital, Denmark

Odense, Denmark

Sector for Hip and Knee Replacement, Dept. of Orthopaedics, Vejle Hospital, Denmark

Vejle, Denmark

Outcomes

Primary Outcomes

Cumulative Survival analysis (Kaplan-Maier survival curve)

Cumulative Survival analysis as time in days without surgery since inclusion

Time frame: one year

Secondary Outcomes

The Hip disability and Osteoarthritis Outcome Score (HOOS 2.0)

HOOS is patient-reported outcome measure with 5 subscales for pain, other symptoms, function in daily living, function in sport and recreation and hip related Quality of Life. A 5-point Likert-scale is used and converted into a 100-point scale with zero indicating the worst possible health (http://www.koos.nu).

Time frame: Baseline, 3 and 12 months

University of California Los Angeles activity score (UCLA)

Physical activity levels in populations. UCLA is a 10-point likert scale recommended and used extensively in similar populations

Time frame: Baseline, 3 and 12 months

Global perceived effect (GPE) score

Patients will be asked to rate possible change in their pain, symptoms, ADL, sports and recreation, quality of life, level of physical activity since the initial administration (baseline) on a 7-point Likert-scale.

Time frame: 3 and 12 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.