The aim of this study is observation of effectiveness and side effect of patients with schizophrenia who will switch the antipsychotics from risperidone long acting injection to paliperidone palmitate.
In this study, investigators are going to enroll the patients who will switch the risperidone long acting injection to paliperidone palmitate. And investigators will examine the effectiveness and side effect of paliperidone palmitate. In addition, effectiveness and side effect related variables will be studied.
Study Type
OBSERVATIONAL
Enrollment
50
Seoul National University Hospital
Seoul, South Korea
Subjective Well-being Under Neuroleptic Treatment (SWN)
Time frame: Change from Baseline in SWN score at 108 weeks
Korean Drug Attitude Inventory-10
Time frame: Change from Baseline in score at 108 weeks
Positive and Negative Syndrome Scale
Time frame: 0,4,8,16,24,36,48,60,72,84,96,108 week
Clinical Global Impression-Severity, Improvement
Time frame: 0,4,8,16,24,36,48,60,72,84,96,108 week
Personal and Social Performance Scale
Time frame: 0,4,8,16,24,36,48,60,72,84,96,108 week
Symptom Check List-90-Revised
Time frame: 0,4,8,16,24,36,48,60,72,84,96,108 week
Drug-Induced ExtraPyramidal Symptoms Scale
Time frame: 0,4,8,16,24,36,48,60,72,84,96,108 week
Liverpool University Neuroleptic Side Effect Rating Scale
Time frame: 0,4,8,16,24,36,48,60,72,84,96,108 week
Visual Analog Scale
injection site pain
Time frame: 0,4,8,16,24,36,48,60,72,84,96,108 week
ECG
electrocardiogram
Time frame: 8, 24, 48, 72, 108 week
blood pressure
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Time frame: 0,4,8,16,24,48,72,108 week
Body weight
Time frame: 0,4,8,16,24,48,72,108 week
waist circumference
Time frame: 0,4,8,16,24,48,72,108 week