Biomarkers in Post-Menopausal Women Receiving Flaxseed

Inclusion Criteria: * Participant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure * Participant must be a non-Hispanic white or non-Hispanic black (self-reported race) woman 45 to 80 years of age and postmenopausal; postmenopausal will be defined as no menstrual cycle in the past 12 months; women with a hysterectomy but with intact ovaries will be included if aged \>= 55 years * Willingness to comply with the requirements of the study Exclusion Criteria: * Unwilling or unable to follow protocol requirements * Self-reported race other than non-Hispanic white or non-Hispanic black * Use, in the 2 months prior to week 1 visit, of antibiotics, hormone replacement therapy, nonprescription hormones or herbal supplements for menopausal symptoms, or flaxseed supplements * Nut or seed allergy * Self-reported inflammatory bowel disease * Gastric bypass * Use of thyroid replacement medication (Synthroid or similar) for \< 1 year * Any condition which in the investigator's opinion deems the participant an unsuitable candidate to receive flaxseed * Chemotherapy/radiation within the past year * Body weight greater than 400 pounds (limit of Tanita scale)