Hemodynamic Changes in Altitude Adaptation

Goethe University12 enrolled

Overview

We use a new technology (Nexfin from BMEYE-Inventive Hemodynamics) to monitor Cardiac Output, Blood Pressure, Fluid Responsiveness, Pulse Oximetry, Hemoglobin Concentration, Oxygen Delivery in Climbers during their process of acclimatization on a expedition to Mount Aconcagua.

Several parameters will be recorded to analyze their influence on the adaptation to high altitude. Such as, food composition, dietary supplements, water intake and output.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Acute Mountain Sickness High Altitude Pulmonary Edema High Altitude Cerebral Edema

Eligibility

Sex: ALLMin age: 20 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * No acute or chronic disease * Body mass index : 20 - 30 Exclusion Criteria: * Any preexisting disease that has a potential impact on physical performance such as: * pulmonary * cerebral * muscular * cardiac * vascular - diseases

Locations (1)

Goethe University

Frankfurt am Main, Hesse, Germany

RECRUITING

Outcomes

Primary Outcomes

Changes from baseline in Oxygen Delivery

Unit: ml/min baseline measure will be obtained at sea level

Time frame: daily, up to 18 days

Secondary Outcomes

Changes from baseline in Hemoglobin Concentration

Unit: mg/dl baseline measure will be obtained at sea level

Time frame: daily, up to 18 days

Data from ClinicalTrials.gov

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