Bronchoscopy is a technique which currently allows the investigation of many respiratory diseases (infections, neoplasia, inflammation…) as well as endobronchial therapeutic procedures. Good flexible bronchoscopy diagnostic practices suggest the use of anxiolytic premedication before endoscopy, but practices concerning the use of sedation further to the completion of the endoscopy are very heterogeneous. We thus propose to compare, during a randomize, controlled trial, respiratory tolerance to I.V. versus sublingual sedation in two groups of patients indergoing bronchoscopy
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
85
Patients who will undergo bronchoscopy will be followed during one day. They will be randomized in the I.V. sedation group
Patients who will undergo bronchoscopy will be followed during one day. They will be randomized in the sublingual sedation group
Cavailles
Nantes, France
Intensity of dyspnea
Intensity of dyspnea assessed by the patient 1h after bronchoscopy in both groups measured by VAS (visual analogue scale) score (in millimeters on a 0 to 100 scale).
Time frame: 1 day
VAS Individual scores
VAS Individual scores performed 1 hour after bronchoscopy (cough, nausea, pain, anxiety, overall tolerance)
Time frame: 1 day
Blood pressure
Blood pressure (mean blood pressure measurements made before, during and after the exam)
Time frame: 1 day
Desaturation frequency
Desaturation frequency during bronchoscopy, defined by the lowering of transcutaneous oxygen saturation below 90%
Time frame: 1 day
heart rate
Initial and maximum heart rate during bronchoscopy (continuous monitoring)
Time frame: 1 day
OAAS Score
OAAS Score after bronchoscopy
Time frame: 1 day
Bronchoscopy duration
Bronchoscopy duration (time difference between the input and output of the examination room, and between the start and end of bronchoscopy)
Time frame: 1 day
Comparison of midazolam total dose
Comparison of midazolam total dose administered in each group
Time frame: 1 day
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.