Influence of Inhaled Anaesthetics on Rebreathing of Carbon Dioxide When Using an Anaesthesia Gas Reflector (AnaConDa)

Region Skane12 enrolled

Overview

The purpose is to investigate how the adsorptive capacity of the active carbon filter to carbon dioxide in an anaesthetic gas reflector (AnaConDa) is affected by adding inhaled anaesthetic agent. The hypothesis is that addition of inhaled anaesthetic agent will affect the amount of adsorption of carbon dioxide to the active carbon and thereby affect rebreathing of carbon dioxide.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Ischemic Heart Disease

Interventions

Inhaled anaesthetic agentOTHER

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * elective coronary artery by-pass graft surgery * elective valve replacement surgery * normal left ventricular ejection fraction on preoperative echocardiography Exclusion Criteria: * obstructive lung disease * restrictive lung disease

Locations (1)

Skane University Hospital Lund, Cardiothoracic Intensive Care

Lund, Sweden

Outcomes

Primary Outcomes

Volume of carbon dioxide rebreathing from an anesthetic gas reflector

Tidal carbon dioxide volume rebreathed from an anesthetic gas reflector correlated to concentration of delivered anesthetic gas.

Time frame: 2 hours

Secondary Outcomes

Quantification of ventilatory requirements to maintain isocapnia with the use of an anesthetic gas reflector.

Changes of tidal volume required to maintain constant alveolar ventilation will be assessed by continuous measurement of exhaled tidal carbon dioxide volume, the latter to be maintained at a constant value.

Time frame: 2 hours

Data from ClinicalTrials.gov

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