Breast Milk Composition and HIV-exposed/Unexposed Early Infant Growth and Infectious Disease Events

Cornell University208 enrolled

Overview

The purpose of this study is to understand how breast milk may protect infants from infection and promote favorable immunological, growth and development outcomes. By following mothers and their infants, we will evaluate the important interactions between infant immune responses and infectious disease events in relation to breast milk composition and feeding patterns. Our aim is to identify a set of predictive factors corresponding to healthy early infant growth and development in this setting in Northern Tanzania.

Study Type

OBSERVATIONAL

Enrollment

208

Conditions

HIV Malnutrition Cryptosporidiosis

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Informed consent provided by mothers, and parental consent on behalf of their infants * Confirmed maternal HIV status (HIV-1, HIV-2 or HIV-Dual seropositive or HIV-seronegative) * Stated intention to remain in the clinic catchment area ≥6 months post-partum * Singleton birth Exclusion Criteria: * None

Locations (1)

Kisesa Health Centre

Outcomes

Primary Outcomes

Breast milk composition

Time frame: Up to 6 months post-partum

Secondary Outcomes

Infant anthropometric measures

Time frame: Up to 6 months of age

Infant infectious disease events

Time frame: Up to 6 months of age