This study is aimed at examining the safety and efficacy of rotational atherectomy (RA) in nondilatable calcified lesion complicated by coronary dissection during percutaneous coronary intervention (PCI) procedure.
Coronary artery dissection is a contraindication for the use of rotational atherectomy, since rotational atherectomy may propagate coronary dissection. In the presence of coronary dissection, conservative management is suggested for approximately 4 weeks to permit the dissection to heal prior to treatment with rotational atherectomy. However, a lot of patients have frequent angina attacks and some patients develop serious complications including abrupt vessel closure during this period. Thus, immediate strategies cope with coronary dissection induced by balloon dilation is needed for the early recovery of those patients. The present study was performed to compare the safety and efficacy of immediate RA and delayed RA in the treatment with nondilatable calcified lesion complicated by coronary dissection.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
198
Immediate RA in the treatment with nondilatable calcified lesion complicated by coronary dissection.
Delayed RA in the treatment with nondilatable calcified lesion complicated by coronary dissection
Xijing Hospital, Fourth Military Medical University
Xi'an, Shaanxi, China
All cause death
cardiac death and non-cardiac death
Time frame: 4 years
Left ventricular ejection fraction (LVEF)
Time frame: 4 years
6-min walk distance (6MWD)
Time frame: 4 years
angina class
angina class according to the Canadian Cardiovascular Society (CCS) classification and Seattle Angina Questionnaire
Time frame: 4 years
Non-fatal myocardial infarction
Time frame: 4 years
Stent thrombosis
Time frame: 4 years
Cardiac tamponade
Time frame: 4 years
Stroke
Time frame: 4 years
Target lesion revascularization
Time frame: 4 years
New York Heart Association (NYHA) class IV heart failure
Time frame: 4 years
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.