Serum Omentin-1 and Carotid Atherosclerosis In Non-Diabetic Chronic Kidney Disease

Kocaeli Derince Education and Research Hospital85 enrolled

Overview

The aim of the study is to evaluate whether a low level of serum omentin-1 is associated with carotid atherosclerosis and mediated by inflammation.

Atherosclerotic cardiovascular disease is markedly increased in chronic kidney disease. There are a lot of risk factor, along with conventional risk factors. Serum onemtin-1 is a adipokine and suggested as a new marker for vascular disease.It has some anti-atherogenic properties. Studies investigating serum omentin-1 level have usually conducted in patients with diabetes mellitus.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Non-diabetic Chronic Kidney Disease Atherosclerosis

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * between ages of 18 - 65 years old chronic kidney disease of stage 3-4 Exclusion Criteria: * Chronic kidney disease of stage 5 * The history of ischemic cardiovascular disease (myocardial infarction, unstable angina, stroke, peripheral artery disease, or cardiovascular revascularization) * Severe heart failure * Stage 2 hypertension * Diabetes mellitus * Corticosteroid therapy * Severe hepatic disease * Smoking * Inflammatory disease * Acute infectious disease * Malignancy

Locations (1)

Department of Nephrology, Check-up Clinic,Kocaeli Derince Education and Traning Hospital

İzmit, Kocaeli, Turkey (Türkiye)

RECRUITING

Data from ClinicalTrials.gov

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